Our Published Reviews and Protocols

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OESOPHAGUS (64)
OTHER (3)
STOMACH (107)
DUODENUM (20)
- Cancer (1)
  - Diagnosis (0)
  - Prevention (0)
  - Treatment (1)
    Chemotherapy (0)
    Surgery (1)
    Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy
- Celiac Disease (0)
  - Diagnosis (0)
  - Prevention (0)
  - Treatment (0)
- Functional Dyspepsia (3)
  - Diagnosis (0)
  - Prevention (0)
    Lifestyle (0)
  - Treatment (3)
    Complementary (1)
    Acupuncture for functional dyspepsia
    Lifestyle (0)
    Pharmacology (2)
    Antidepressants and anxiolytics for functional dyspepsia
    Prokinetics for functional dyspepsia
- Ulcer (Complicated) (11)
- Ulcer (Uncomplicated) (3)
  - Diagnosis (0)
  - Prevention (1)
    Pharmacology (1)
    Prevention of NSAID-induced gastroduodenal ulcers
  - Treatment (2)
    Nutritional (1)
    Fasting for haemostasis in children with gastrointestinal bleeding
    Pharmacology (1)
    Eradication therapy for peptic ulcer disease in -positive people
- Other Duodenal Disorders (2)
  - Diagnosis (0)
  - Prevention (1)
    Nutritional (0)
    Surgery (1)
    Enhanced recovery protocols for major upper gastrointestinal, liver and pancreatic surgery
  - Treatment (1)
    Pharmacology (1)
    Efficacy of thalidomide in management of bleeding from gastrointestinal angiodysplasia
PANCREAS (95)
BOWEL (196)
- Abdominal migraine (1)
  - Probiotics (1)
    Probiotics for management of functional abdominal pain disorders in children
- CROHN'S DISEASE - INDUCTION OF REMISSION (41)
  - Adalimumab (1)
    Adalimumab for the treatment of active Crohn's disease
  - Adjuvant therapy with antidepressants (1)
    Antidepressants for inflammatory bowel disease
  - Aminosalicylates (1)
    Aminosalicylates for treatment of active Crohn's disease
  - Anti-IL-12/23 (1)
    Ustekinumab and briakinumab for the treatment of active Crohn's disease
  - Anti-IL-17 (0)
  - Anti-drug antibodies (1)
    Antibody development against biologic agents used for the treatment of inflammatory bowel disease and antibody prevention with immunosuppressives
  - BCG vaccine (0)
  - Biosimilar infliximab (1)
    Effectiveness and safety of switching IBD patients from the originator to the biosimilar infliximab
  - Budesonide therapy (1)
    Budesonide for treatment of people with active Crohn's disease.
  - 5-aminosalicylate therapy (0)
  - Azathioprine or 6-mercaptopurine therapy (1)
    Azathioprine or 6-mercaptopurine for the treatment of active Crohn's disease
  - Antibiotic therapy (1)
    Antibiotics for the treatment of Crohn's disease
  - Cannabis (1)
    Cannabis and cannabis oil for the treatment of Crohn's disease
  - Certolizumab pegol (1)
    Certolizumab pegol for the treatment of active Crohn’s disease
  - Corticosteroid therapy (1)
    Corticosteroids for induction of remission in Crohn's disease
  - Dietary interventions (1)
    Diets for inducing and maintaining remission in inflammatory bowel disease (IBD)
  - Enteral nutritional therapy (1)
    Enteral nutritional therapy for treatment of active Crohn's disease
  - Glutamine (1)
    Glutamine for treatment of active Crohn's disease
  - Helminths (1)
    Helminth therapy (worms) for induction of remission in inflammatory bowel disease
  - Herbal medicines (1)
    Herbal medicines for the treatment of inflammatory bowel disease
  - Humanized antibody to alpha4beta7 integrin (0)
  - Influenza vaccination (0)
  - Interventions for fatigue (1)
    Treatments for extreme tiredness and lack of energy (fatigue) in inflammatory bowel disease
  - Interventions to treat strictures (0)
  - Low dose naltrexone (1)
    Low dose naltrexone for treatment of active Crohn’s disease
  - Mucosal healing (0)
  - Mycophenolate mofetil (0)
  - Pain management (1)
    Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease
  - Parenteral nutritional therapy (0)
  - Methotrexate therapy (1)
    Methotrexate for treatment of active treatment resistant Crohn's disease
  - Cyclosporine therapy (1)
    Cyclosporine for treatment of active Crohn's disease
  - Placebo (0)
  - Prevention of hospitalization and surgery (0)
  - Psychological interventions (1)
    Psychological interventions in inflammatory bowel disease
  - Quality of life (1)
    The impact of biological interventions on health-related quality of life in adults with Crohn's disease
  - Recombinant human growth hormone (somatropin) (0)
  - Sargramostim (GM-CSF) (1)
    Sargramostim (GM-CSF) for induction of remission in Crohn's disease
  - Stem cell transplantation (1)
    Stem cell transplantation for induction of remission in medically refractory Crohn’s disease
  - Surgical therapy and female fertility (1)
    The risk of infertility in women with IBD who have had surgery
  - Tacrolimus (0)
  - Thalidomide (1)
    Thalidomide for induction of remission in Crohn's disease
  - Tumor necrosis factor-alpha therapy (3)
    Biologic drugs for induction and maintenance of remission in Crohn's disease: a network meta-analysis
    Infliximab for medical induction of remission in Crohn's disease
    Tumor necrosis factor-alpha antibody for induction of remission in Crohn's disease
  - Probiotics (1)
    Probiotics for induction of remission in Crohn's disease
  - Recombinant human interleukin 10 (1)
    Interleukin 10 (IL-10) for induction of remission in Crohn's disease
  - Natalizumab (1)
    Natalizumab for treatment of active Crohn's disease
  - Validation of MRI scoring indices (1)
    MRI scoring indices for evaluation of disease activity and severity in Crohn’s disease
  - Validation of endoscopic scoring indices (1)
    Endoscopic scoring indices for evaluation of disease activity in Crohn's disease
  - Validation of histologic scoring indices (1)
    Histologic measurement tools for evaluation of disease activity in Crohn’s disease
  - Vedolizumab (2)
    Biologic drugs for induction and maintenance of remission in Crohn's disease: a network meta-analysis
    Vedolizumab for induction and maintenance of remission in Crohn's disease
  - Vitamin D (1)
    Vitamin D for the treatment of inflammatory bowel disease
  - postoperative infectious complications (1)
    Risk of postoperative infectious complications from medical therapies in inflammatory bowel disease
- CROHN'S DISEASE - MAINTENANCE OF REMISSION (41)
  - Adalimumab (1)
    Adalimumab for maintenance of remission in Crohn's disease
  - Adjuvant therapy with antidepressants (1)
    Antidepressants for inflammatory bowel disease
  - Anti-IL-12/23p40 antibodies (1)
    Ustekinumab and briakinumab for the treatment of inactive Crohn's disease
  - Anti-drug antibodies (1)
    Antibody development against biologic agents used for the treatment of inflammatory bowel disease and antibody prevention with immunosuppressives
  - Antibiotic therapy (1)
    Antibiotics for the treatment of Crohn's disease
  - Biosimilar infliximab (1)
    Effectiveness and safety of switching IBD patients from the originator to the biosimilar infliximab
  - Cannabis (1)
    Cannabis and cannabis oil for the treatment of Crohn's disease
  - Certolizumab pegol (1)
    Certolizumab pegol for maintenance of medically induced remission in Crohn’s disease
  - Colonoscopic surveillance (1)
    Colonoscopy-guided therapy for the prevention of post-operative recurrence of Crohn’s disease
  - Corticosteroid therapy (1)
    Corticosteroids for maintenance of remission in Crohn's disease
  - Budesonide therapy (1)
    Budesonide for maintenance of remission in Crohn's disease
  - 5-aminosalicylate therapy, topical and oral (2)
    Oral 5-aminosalicylic acid drugs for maintenance of medically-induced remission in Crohn's disease
    Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn’s disease
  - Azathioprine or 6-mercaptopurine therapy (3)
    6-thioguanine nucleotide monitoring in azathioprine and mercaptopurine monotherapy for the treatment of inflammatory bowel disease
    Azathioprine and 6-mercaptopurine for the maintenance of surgically-induced remission in Crohn’s disease
    Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease
  - Cyclosporine therapy (0)
  - Dietary interventions (1)
    Diets for inducing and maintaining remission in inflammatory bowel disease (IBD)
  - Fish oil (1)
    Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease
  - Herbal medicines (1)
    Herbal medicines for the treatment of inflammatory bowel disease
  - Infliximab (1)
    Infliximab for maintenance of medically-induced remission in Crohn's disease
  - Influenza vaccination (0)
  - Interventions for fatigue (1)
    Treatments for extreme tiredness and lack of energy (fatigue) in inflammatory bowel disease
  - Interventions to treat strictures (0)
  - Methotrexate therapy (1)
    Methotrexate for treatment of inactive Crohn's disease
  - Anti-tuberculous therapy (1)
    Anti-tuberculous therapy for maintaining remission in Crohn's disease
  - Enteral nutritional therapy (1)
    Enteral nutrition (liquid feeds) for maintenance of remission in Crohn's disease
  - Mucosal healing (0)
  - Oral Janus kinase inhibitors (0)
  - Pain management (1)
    Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease
  - Placebo (0)
  - Post-operative recurrence (2)
    Interventions for maintaining surgically included remission in Crohn's disease
    Interventions for prevention of post-operative recurrence of Crohn's disease
  - Prevention of bone disease (0)
  - Prevention of hospitalization and surgery (0)
  - Prevention of hospitalization or surgery (0)
  - Psychological interventions (1)
    Psychological interventions in inflammatory bowel disease
  - Quality of life (1)
    The impact of biological interventions on health-related quality of life in adults with Crohn's disease
  - Selective cyclooxygenase 2 inhibitors for treatment of rheumatological manifestations (1)
    Tolerability of selective cyclooxygenase 2 (COX-2) inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease
  - Surgical therapy and female fertility (1)
    The risk of infertility in women with IBD who have had surgery
  - Thalidomide (1)
    Thalidomide for maintenance of remission in Crohn's disease
  - Therapy for perianal disease and fistulae (0)
  - Probiotics (1)
    Probiotics for maintenance of remission in Crohn's disease
  - Recombinant human interleukin (0)
  - Tumor necrosis factor-alpha therapy (2)
    Biologic drugs for induction and maintenance of remission in Crohn's disease: a network meta-analysis
    Tumor necrosis factor-alpha antibody for maintenance of remission in Crohn's disease
  - Validation of MRI scoring indices (1)
    MRI scoring indices for evaluation of disease activity and severity in Crohn’s disease
  - Validation of endoscopic scoring indices (1)
    Endoscopic scoring indices for evaluation of disease activity in Crohn's disease
  - Validation of histologic scoring indices (1)
    Histologic measurement tools for evaluation of disease activity in Crohn’s disease
  - Vedolizumab (1)
    Biologic drugs for induction and maintenance of remission in Crohn's disease: a network meta-analysis
  - Vitamin D (1)
    Vitamin D for the treatment of inflammatory bowel disease
  - Withdrawal of drug therapy (1)
    Is withdrawal of drug therapy feasible in patients with CD who have achieved remission?
- Diagnostic Test Accuracy (1)
  - Biomarkers for assessing disease activity in inflammatory bowel disease
- Functional abdominal pain disorders (1)
  - Probiotics (1)
    Probiotics for management of functional abdominal pain disorders in children
- Infliximab (0)
- ULCERATIVE COLITIS - INDUCTION OF REMISSION (40)
  - Adjuvant therapy with antidepressants (1)
    Antidepressants for inflammatory bowel disease
  - Alicaforsen (0)
  - Anti-MAdCAM antibody (1)
    Anti-MAdCAM antibody for induction of remission in ulcerative colitis
  - Anti-drug antibodies (1)
    Antibody development against biologic agents used for the treatment of inflammatory bowel disease and antibody prevention with immunosuppressives
  - Antibiotics (1)
    Antibiotics for the induction and maintenance of remission in ulcerative colitis
  - Biosimilar infliximab (1)
    Effectiveness and safety of switching IBD patients from the originator to the biosimilar infliximab
  - Cannabis (1)
    Cannabis and cannabis oil for the treatment of ulcerative colitis
  - Dietary interventions (1)
    Diets for inducing and maintaining remission in inflammatory bowel disease (IBD)
  - Etrolizumab (1)
    Etrolizumab for the treatment of active ulcerative colitis
  - Fecal transplantation (1)
    Fecal transplantation for treatment of inflammatory bowel disease
  - Fish oil (1)
    Fish oil for the treatment of active ulcerative colitis
  - Helminths (1)
    Helminth therapy (worms) for induction of remission in inflammatory bowel disease
  - Heparin (1)
    Unfractionated or low molecular weight heparin for treatment of active ulcerative colitis
  - Herbal medicines (1)
    Herbal medicines for the treatment of inflammatory bowel disease
  - Humanized antibody to alpha4beta7 integrin (1)
    Vedolizumab for the treatment of active and inactive ulcerative colitis
  - Influenza vaccination (0)
  - Interferons (1)
    Type I interferons for treatment of active ulcerative colitis
  - Interventions for fatigue (1)
    Treatments for extreme tiredness and lack of energy (fatigue) in inflammatory bowel disease
  - Methotrexate (1)
    Methotrexate for treatment of chronic active ulcerative colitis
  - Mucosal healing (0)
  - Oral janus kinase inhibitors (1)
    Oral janus kinase inhibitors for induction of remission in ulcerative colitis
  - Pain management (1)
    Interventions for the management of abdominal pain in ulcerative colitis
  - Placebo (1)
    Placebo response and remission rates in randomised trials of induction and maintenance therapy for ulcerative colitis
  - Prebiotics (1)
    Prebiotics for induction and maintenance of remission in ulcerative colitisNew
  - Psychological interventions (1)
    Psychological interventions in inflammatory bowel disease
  - Quality of life (1)
    The impact of biological interventions for ulcerative colitis on health-related quality of life
  - Short chain fatty acids (0)
  - Surgical therapy and female fertility (1)
    The risk of infertility in women with IBD who have had surgery
  - Tacrolimus (1)
    Tacrolimus (FK506) for induction of remission in corticosteroid-refractory ulcerative colitis
  - Topical corticosteroid therapy (1)
    Rectal corticosteroids for induction of remission in ulcerative colitis
  - Oral corticosteroid therapy (1)
    Oral corticosteroids for induction of remission in ulcerative colitis
  - Budesonide therapy (1)
    Oral budesonide for treatment of people with active ulcerative colitis
  - 5-ASA therapy, topical and oral (2)
    5-ASA suppositories, enemas or foam for induction of remission in ulcerative colitis
    Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis
  - Cyclosporine therapy (1)
    Cyclosporine A for induction of remission in severe ulcerative colitis
  - Active pouchitis (1)
    Therapy for treatment and prevention of pouchitis
  - Parenteral nutritional therapy (0)
  - Traditional Chinese medicinal herbs (0)
  - Tumor necrosis factor-alpha therapy (1)
    Tumour necrosis factor alpha blocking agents for treatment of active ulcerative colitis
  - Probiotics (1)
    Probiotics for the treatment of active ulcerative colitis
  - Transdermal nicotine (1)
    Transdermal nicotine for the treatment of active ulcerative colitis
  - Azathioprine (0)
  - Validation of endoscopic scoring indices (1)
    Endoscopic scoring indices for evaluation of disease activity in ulcerative colitis
  - Validation of histologic scoring indices (1)
    Histologic measurement tools for evaluating disease in ulcerative colitis patients
  - Vedolizumab (1)
    Vedolizumab for the treatment of active and inactive ulcerative colitis
  - Vitamin D (1)
    Vitamin D for the treatment of inflammatory bowel disease
  - postoperative infectious complications (1)
    Risk of postoperative infectious complications from medical therapies in inflammatory bowel disease
- ULCERATIVE COLITIS - MAINTENANCE OF REMISSION (30)
  - Adjuvant therapy with antidepressants (1)
    Antidepressants for inflammatory bowel disease
  - Anti-drug antibodies (1)
    Antibody development against biologic agents used for the treatment of inflammatory bowel disease and antibody prevention with immunosuppressives
  - Antibiotics (1)
    Antibiotics for the induction and maintenance of remission in ulcerative colitis
  - Biosimilar infliximab (1)
    Effectiveness and safety of switching IBD patients from the originator to the biosimilar infliximab
  - Cannabis (1)
    Cannabis and cannabis oil for the treatment of ulcerative colitis
  - Corticosteroid therapy (1)
    Rectal corticosteroids for maintenance of remission in ulcerative colitis
  - 5-aminosalicylate therapy (2)
    Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis
    Rectal 5-aminosalicylic acid (suppository, foam or liquid enema) for maintenance of remission in ulcerative colitis
  - Azathioprine and 6-mercaptopurine therapy (2)
    6-thioguanine nucleotide monitoring in azathioprine and mercaptopurine monotherapy for the treatment of inflammatory bowel disease
    Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis
  - Cancer surveillance in IBD (1)
    Strategies for detecting colon cancer in patients with inflammatory bowel disease
  - Curcumin (1)
    Curcumin for maintenance of remission in ulcerative colitis
  - Dietary interventions (1)
    Diets for inducing and maintaining remission in inflammatory bowel disease (IBD)
  - Fecal transplantation (1)
    Fecal transplantation for treatment of inflammatory bowel disease
  - Fish oil (1)
    Omega 3 fatty acids for maintenance of remission in ulcerative colitis
  - Herbal medicines (1)
    Herbal medicines for the treatment of inflammatory bowel disease
  - Influenza vaccination (0)
  - Interventions for fatigue (1)
    Treatments for extreme tiredness and lack of energy (fatigue) in inflammatory bowel disease
  - Methotrexate (1)
    Methotrexate for keeping ulcerative colitis inactive
  - Mucosal healing (0)
  - Oral Janus kinase inhibitors (1)
    Oral Janus kinase inhibitors for maintenance of remission in ulcerative colitis
  - Pain management (1)
    Interventions for the management of abdominal pain in ulcerative colitis
  - Placebo (1)
    Placebo response and remission rates in randomised trials of induction and maintenance therapy for ulcerative colitis
  - Prevention of bone disease (0)
  - Probiotics (1)
    Probiotics for maintenance of remission in ulcerative colitis
  - Psychological interventions (1)
    Psychological interventions in inflammatory bowel disease
  - Quality of life (1)
    The impact of biological interventions for ulcerative colitis on health-related quality of life
  - Selective cyclooxygenase 2 inhibitors for treatment of rheumatological manifestations (1)
    Tolerability of selective cyclooxygenase 2 (COX-2) inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease
  - Surgical therapy and female fertility (1)
    The risk of infertility in women with IBD who have had surgery
  - Transdermal nicotine (0)
  - Tumor necrosis alpha therapy (0)
  - Validation of endoscopic scoring indices (1)
    Endoscopic scoring indices for evaluation of disease activity in ulcerative colitis
  - Validation of histologic scoring indices (1)
    Histologic measurement tools for evaluating disease in ulcerative colitis patients
  - Vedolizumab (1)
    Vedolizumab for the treatment of active and inactive ulcerative colitis
  - Vitamin D (1)
    Vitamin D for the treatment of inflammatory bowel disease
- Irritable Bowel Syndrome (14)
  - 5-aminosalicylate therapy (1)
    5-aminosalicylic acid analogues for treatment of irritable bowel syndrome
  - Antibiotics (1)
    Antibiotics for treatment of irritable bowel syndrome in adults
  - Antidepressants (1)
    Antidepressants for functional abdominal pain disorders in children and adolescents
  - Biofeedback (1)
    Biofeedback for the treatment of irritable bowel syndrome
  - Bulking agents, antispasmodics and antidepressant medication (1)
    Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome
  - Calcium channel blockers (0)
  - Herbal medicines (1)
    Herbal medicines for treatment of irritable bowel syndrome
  - Homeopathy (1)
    Homeopathy for treatment of irritable bowel syndrome
  - Loperamide (0)
  - Low FODMAP diet (0)
  - Physical activity (1)
    Physical activity for treatment of irritable bowel syndrome
  - Psychological treatments (1)
    Psychological treatments for the management of irritable bowel syndrome
  - Tegaserod (1)
    Tegaserod for the treatment of irritable bowel syndrome and chronic constipation
  - Prokinetic drugs (0)
  - Acupuncture (1)
    Acupuncture for irritable bowel syndrome
  - Hypnotherapy (1)
    Hypnotherapy (treatment by hypnosis) for the treatment of irritable bowel syndrome
  - Probiotic agents (2)
    Probiotics for management of functional abdominal pain disorders in children
    Probiotics for the treatment of irritable bowel syndrome in children
- Chronic constipation (9)
  - Abdominal massage (1)
    Abdominal massage for the treatment of constipation
  - Acupuncture (1)
    Acupuncture for chronic constipation
  - Antibiotics (0)
  - Antidepressants (1)
    Antidepressants for functional abdominal pain disorders in children and adolescents
  - Biofeedback therapy (1)
    Biofeedback (use of equipment to retrain the muscles around the anus and coordinated pushing) for the treatment of chronic constipation in adults
  - Botulinum toxin (0)
  - Fiber and bulking agents (1)
    Fiber and bulking agents for the treatment of chronic constipation
  - Herbal medicines (0)
  - Linaclotide (0)
  - Management of constipation in the elderly and chronically ill (0)
  - Polyethylene glycol (0)
  - Probiotics (1)
    Probiotics for treatment of chronic constipation in children
  - Prucalopride (1)
    Prucalopride for the treatment of chronic constipation
  - Reflexology (1)
    Reflexology for treatment of constipation
  - Tegaserod (1)
    Tegaserod for the treatment of irritable bowel syndrome and chronic constipation
- OTHER (18)
  - Childhood constipation and soiling (4)
    Laxatives for the management of childhood constipation
    Stimulant laxatives for constipation and soiling in children
    Transcutaneous electrical stimulation (TES) for treating long-term constipation in children.
    Treatments for intractable constipation in childhood
  - Collagenous colitis (1)
    Treatments for collagenous colitis
  - Enterocutaneous fistula (0)
  - Growth failure in Crohn's disease (1)
    Interventions for growth failure in childhood Crohn's disease
  - Hirschsprung-associated enterocolitis (1)
    Probiotics for the prevention of Hirschsprung-associated enterocolitis
  - Inflammatory bowel disease (3)
    Patient education interventions for the management of inflammatory bowel disease
    Remote care through telehealth for people with inflammatory bowel disease
    Interventions for treating iron deficiency anaemia in inflammatory bowel disease
  - Radiation colitis, enteritis and proctitis (0)
  - Clostridium difficile-associated diarrhea (2)
    Antibiotic therapy for Clostridium difficile-associated diarrhoea in adults
    The use of probiotics to prevent Clostridium difficile diarrhea associated with antibiotic use
  - Clostridium difficile-associated colitis (1)
    Probiotics for treatment of Clostridium difficile -associated colitis in adults
  - Antibiotic-associated diarrhea (1)
    Probiotics for the prevention of antibiotic-associated diarrhea in children
  - Lymphocytic colitis (1)
    Treatments for lymphocytic colitis
  - Short bowel syndrome (2)
    Human growth hormone and glutamine for patients with short bowel syndrome
    Teduglutide for the treatment of patients with short bowel syndrome
  - Specialist nursing interventions (1)
    Specialist nurse counselling interventions for patients with inflammatory bowel disease
  - Symptomatic uncomplicated diverticular disease (SUDD) (0)