Review: Extended lymph node resection versus standard resection for pancreatic and periampullary adenocarcinoma

Pancreatic and periampullary adenocarcinomas account for some of the most aggressive malignancies, and the leading causes of cancerÔÇÉrelated mortalities. Partial pancreaticoduodenectomy (PD) with negative resection margins is the only potentially curative therapy. The high prevalence of lymph node metastases has led to the hypothesis that wider excision with the removal of more lymphatic tissue could result in an improvement of survival, and higher rates of negative resection margins.

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