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Ulcerative colitis (UC) is a chronic inflammation of the colon characterised by periods of relapse and remission. It starts in the rectum and can extend throughout the colon. UC and Crohn’s disease (CD) are the most common inflammatory bowel diseases (IBDs). However, UC tends to be more common than CD. It has no known cure but can be managed with...
January 18 2022
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This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To compare the efficacy and safety the anterior and posterior mediastinal reconstruction routes after esophagectomy in patients with esophageal cancer.Read the full protocol here.
December 3 2021
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Crohn's disease is a remitting and relapsing disorder that can affect the whole gastrointestinal tract. Active disease symptoms include abdominal pain, fatigue, weight loss, and diarrhoea. There is no known cure; however, the disease can be managed, and therefore places a huge financial burden on healthcare systems. Abdominal pain is a common and...
November 30 2021
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If you want the latest updates from Cochrane Gut, including new publications, events, opportunities, and news, please sign-up for our quarterly newsletter. Details here. You can read the latest issue (Fall 2021) here.
November 12 2021
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This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To assess the benefits and harms of preservation of the azygos vein versus ligation of the azygos vein during primary surgical repair of congenital esophageal atresia.Read the full protocol here.
November 2 2021
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This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To determine the efficacy and safety of a 6‐thioguanine nucleotide (6‐TGN) metabolite‐based dosing strategy for maintenance of remission using azathioprine or mercaptopurine in Crohn's disease and ulcerative colitis.Read the full protocol here.
November 2 2021
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This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To compare the efficacy and safety of neoadjuvant chemotherapy or chemoradiotherapy versus upfront surgery alone in patients with resectable or borderline resectable pancreatic cancer.Read the full protocol here.
October 29 2021
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This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To assess the effects of adjuvant chemotherapy following curative‐intent resection of ampullary adenocarcinoma on survival, quality of life, adverse events and toxicity.Read the full protocol here.
October 6 2021
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The main goal of enteral nutrition (EN) is to manage malnutrition in order to improve clinical outcomes. However, EN may increase the risks of vomiting or aspiration pneumonia during gastrointestinal dysfunction. Consequently, monitoring of gastric residual volume (GRV), that is, to measure GRV periodically and modulate the speed of enteral...
September 29 2021
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This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To assess the efficacy and safety of plastic stents and metal stents in individuals undergoing endoscopic ultrasound‐guided transmural drainage of pancreatic fluid collections.Read the full version here.
September 29 2021
Ulcerative colitis (UC) is a chronic inflammation of the colon characterised by periods of relapse and remission. It starts in the rectum and can extend throughout the colon. UC and Crohn’s disease (CD) are the most common inflammatory bowel diseases (IBDs). However, UC tends to be more common than CD. It has no known cure but can be managed with...January 18 2022
This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To compare the efficacy and safety the anterior and posterior mediastinal reconstruction routes after esophagectomy in patients with esophageal cancer.Read the full protocol here.December 3 2021
Crohn's disease is a remitting and relapsing disorder that can affect the whole gastrointestinal tract. Active disease symptoms include abdominal pain, fatigue, weight loss, and diarrhoea. There is no known cure; however, the disease can be managed, and therefore places a huge financial burden on healthcare systems. Abdominal pain is a common and...November 30 2021
If you want the latest updates from Cochrane Gut, including new publications, events, opportunities, and news, please sign-up for our quarterly newsletter. Details here. You can read the latest issue (Fall 2021) here.November 12 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To assess the benefits and harms of preservation of the azygos vein versus ligation of the azygos vein during primary surgical repair of congenital esophageal atresia.Read the full protocol here.November 2 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To determine the efficacy and safety of a 6‐thioguanine nucleotide (6‐TGN) metabolite‐based dosing strategy for maintenance of remission using azathioprine or mercaptopurine in Crohn's disease and ulcerative colitis.Read the full protocol here.November 2 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To compare the efficacy and safety of neoadjuvant chemotherapy or chemoradiotherapy versus upfront surgery alone in patients with resectable or borderline resectable pancreatic cancer.Read the full protocol here.October 29 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To assess the effects of adjuvant chemotherapy following curative‐intent resection of ampullary adenocarcinoma on survival, quality of life, adverse events and toxicity.Read the full protocol here.October 6 2021
The main goal of enteral nutrition (EN) is to manage malnutrition in order to improve clinical outcomes. However, EN may increase the risks of vomiting or aspiration pneumonia during gastrointestinal dysfunction. Consequently, monitoring of gastric residual volume (GRV), that is, to measure GRV periodically and modulate the speed of enteral...September 29 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows:To assess the efficacy and safety of plastic stents and metal stents in individuals undergoing endoscopic ultrasound‐guided transmural drainage of pancreatic fluid collections.Read the full version here.September 29 2021